Product Name :
CCR1 antagonist 9
Description:
CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50 of 6.8 nM in calcium flux assay.
CAS:
1220026-26-5
Molecular Weight:
425.44
Formula:
C20H16FN5O3S
Chemical Name:
1-(4-fluorophenyl)-N-[(2-methanesulfonylpyridin-4-yl)methyl]-1H-pyrazolo[3,4-c]pyridine-4-carboxamide
Smiles :
CS(=O)(=O)C1=CC(CNC(=O)C2=CN=CC3=C2C=NN3C2C=CC(F)=CC=2)=CC=N1
InChiKey:
DCHROQCNJDJPGN-UHFFFAOYSA-N
InChi :
InChI=1S/C20H16FN5O3S/c1-30(28,29)19-8-13(6-7-23-19)9-24-20(27)17-10-22-12-18-16(17)11-25-26(18)15-4-2-14(21)3-5-15/h2-8,10-12H,9H2,1H3,(H,24,27)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50 of 6.{{Degarelix} MedChemExpress|{Degarelix} Apoptosis|{Degarelix} Biological Activity|{Degarelix} Description|{Degarelix} manufacturer|{Degarelix} Cancer} 8 nM in calcium flux assay.{{Chlorthalidone} web|{Chlorthalidone} Purity & Documentation|{Chlorthalidone} Data Sheet|{Chlorthalidone} custom synthesis|{Chlorthalidone} Epigenetics} |Product information|CAS Number: 1220026-26-5|Molecular Weight: 425.PMID:23912708 44|Formula: C20H16FN5O3S|Chemical Name: 1-(4-fluorophenyl)-N-[(2-methanesulfonylpyridin-4-yl)methyl]-1H-pyrazolo[3,4-c]pyridine-4-carboxamide|Smiles: CS(=O)(=O)C1=CC(CNC(=O)C2=CN=CC3=C2C=NN3C2C=CC(F)=CC=2)=CC=N1|InChiKey: DCHROQCNJDJPGN-UHFFFAOYSA-N|InChi: InChI=1S/C20H16FN5O3S/c1-30(28,29)19-8-13(6-7-23-19)9-24-20(27)17-10-22-12-18-16(17)11-25-26(18)15-4-2-14(21)3-5-15/h2-8,10-12H,9H2,1H3,(H,24,27)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 83.33 mg/mL (195.87 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|CCR1 antagonist 9 (Compound 19e) blocks the CCR1 chemotaxis of THP-1 cells with an IC50 of 28 nM. CCR1 antagonist 9 also blocks hERG with an IC50 of 30 μM.|Products are for research use only. Not for human use.|
