Product Name :
Anti-TROP2, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human/Cynomolgus
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-TROP-2, Human antibody is designed for detecting human TROP-2 specifically. Anti-TROP-2, Human antibody is recombinant VHH domain of alpaca IgG2b/2c fused to human IgG1 Fc. Based on ELISA, Anti-TROP-2, Human antibody reacts with human TROP-2, and has reactivity with cynomolgus TROP-2. | Immunogen: Recombinant human TROP-2 | Host: Alpaca pacous | Isotype: VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation) | Conjugate: Unconjugated | Specificity: Human TROP-2 | Cross-Reactivity: Cross-reactivity with cynomolgus TROP-2 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles), Stable for 12 months at -20°C | Background:TROP-2, also named tumor-associated calcium signal transducer 2 (TACSTD2), GA733 tumor associated antigen, and epithelial glycoprotein-1 (EGP-1), is a type I transmembrane protein highly expressed in carcinomas. This antigen is a member of a family including at least two type I membrane proteins.{{1855925-27-7} MedChemExpress|{1855925-27-7} Protocol|{1855925-27-7} Purity|{1855925-27-7} custom synthesis} It transduces an intracellular calcium signal and acts as a cell surface receptor.{{97322-87-7} web|{97322-87-7} Purity & Documentation|{97322-87-7} References|{97322-87-7} supplier} Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.PMID:29939635 Using antibody with Fc(mutation), the background from Fc receptors will be eliminated.
Description2 :
Anti-TROP-2, Human antibody is designed for detecting human TROP-2 specifically. Anti-TROP-2, Human antibody is recombinant VHH domain of alpaca IgG2b/2c fused to human IgG1 Fc. Based on ELISA, Anti-TROP-2, Human antibody reacts with human TROP-2, and has reactivity with cynomolgus TROP-2.
Immunogen:
Recombinant human TROP-2
Host :
Alpaca pacous
Isotype:
VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation)
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles), Stable for 12 months at -20°C
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.
