Product Name :
4, 4′-Dimethoxybenzil
Description:
4,4′-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM.
CAS:
1226-42-2
Molecular Weight:
270.28
Formula:
C16H14O4
Chemical Name:
bis(4-methoxyphenyl)ethane-1,2-dione
Smiles :
COC1C=CC(=CC=1)C(=O)C(=O)C1C=CC(=CC=1)OC
InChiKey:
YNANGXWUZWWFKX-UHFFFAOYSA-N
InChi :
InChI=1S/C16H14O4/c1-19-13-7-3-11(4-8-13)15(17)16(18)12-5-9-14(20-2)10-6-12/h3-10H,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Linperlisib} site|{Linperlisib} PI3K|{Linperlisib} Technical Information|{Linperlisib} In stock|{Linperlisib} manufacturer|{Linperlisib} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
4,4′-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM.|Product information|CAS Number: 1226-42-2|Molecular Weight: 270.28|Formula: C16H14O4|Chemical Name: bis(4-methoxyphenyl)ethane-1,2-dione|Smiles: COC1C=CC(=CC=1)C(=O)C(=O)C1C=CC(=CC=1)OC|InChiKey: YNANGXWUZWWFKX-UHFFFAOYSA-N|InChi: InChI=1S/C16H14O4/c1-19-13-7-3-11(4-8-13)15(17)16(18)12-5-9-14(20-2)10-6-12/h3-10H,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (184.{{Streptavidin Protein} site|{Streptavidin Protein} Purity & Documentation|{Streptavidin Protein} In Vitro|{Streptavidin Protein} manufacturer|{Streptavidin Protein} Cancer} 99 mM; Need ultrasonic).PMID:33183092 H2O : Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|By reducing irinotecaninduced diarrhea, hiCE inhibitors (e.g., 4,4′-Dimethoxybenzil, Compound 8) can improve the anti-cancer efficacy of irinotecan. To find effective hiCE inhibitors, a new virtual screening protocol that combines pharmacophore models derived from the hiCE structure and its ligands has been proposed.|Products are for research use only. Not for human use.|
