Product Name: C4BPA Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Rat
Conjugation: ALEXA FLUOR® 594
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human C4a
Clonality: Polyclonal
CAS NO: 1453848-26-4
Product: Panobinostat
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: C4b-binding protein alpha chain; C4bp; C4bpa; C4BPA_HUMAN; Complement component 4 binding protein; Proline-rich protein; PrP; RP11-164O23.4.
Background: C4BPA is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.
PubMed ID:http://jpet.aspetjournals.org/content/275/3/1527
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