Product Name: Cappuccino Polyclonal Antibody, Cy3 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy3
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human CNO/Cappuccino
Clonality: Polyclonal
CAS NO: 145-41-5
Product: Magnolol
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Cappuccino; Cappuccino homolog; Cappuccino homolog; FLJ11230; Protein cappuccino; Protein cappuccino homolog; BL1S4_HUMAN; Biogenesis of lysosome-related organelles complex 1 subunit 4; BLOC-1 subunit 4; BLOC1S4; BCAS4L; CNO.
Background: Biogenesis of lysosome-related organelles complex-1 (BLOC-1) is a multisubunit protein necessary for biogenesis of specialized organelles of the endosomal-lysosomal system (such as melanosomes and platelet-dense granules). The complex consists of coiled-coil-forming proteins Snapin, Pallidin, Cappuccino, Muted, BLOS1, BLOS2, and BLOS3. The localization of these proteins varies as they can be cytoplasmic, peripheral membrane bound or anchored to the vesicular membrane.Cappuccino, a primarily cytoplasmic protein, plays a role in the development of melanosomes, platelet-dense granules and other lysosome-related organelles. It interacts primarily with pallidin and Muted and has been implicated as an actin-nucleation factor that may play a role in crosstalk between microfilaments and microtubules.
PubMed ID:http://jpet.aspetjournals.org/content/291/2/464
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