Product Name: CARD17 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: ALEXA FLUOR® 488
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human CARD17/INCA
Clonality: Polyclonal
CAS NO: 1098-60-8
Product: AF-353
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: CAR17_HUMAN; CARD 17; CARD17; Caspase 1 inhibitor; Caspase recruitment domain containing protein 17; Caspase recruitment domain-containing protein 17; Caspase-1 inhibitor INCA; Caspase1 inhibitor; Inhibitory caspase recruitment domain CARD protein; Inhibitory caspase recruitment domain protein.
Background: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
PubMed ID:http://jpet.aspetjournals.org/content/292/1/261
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