Product Name: Caspase-1 p20 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: ALEXA FLUOR® 350
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human Caspase-1 p20
Clonality: Polyclonal
CAS NO: 1261079-38-2
Product: BI605906
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Caspase-1 subunit p20; Caspase-1; CASP-1; IL-1 beta-converting enzyme; Interleukin-1 beta-converting enzyme; IL1BC; IL1BCE; CASP1
Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
PubMed ID:http://jpet.aspetjournals.org/content/294/3/1131
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