Product Name: Caspase-7 Polyclonal Antibody
Applications: WB, IHC-P, IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human Caspase-7
Clonality: Polyclonal
CAS NO: 366017-09-6
Product: Dibenzothiophene
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Synonyms: MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3; Caspase-7; Apoptotic protease Mch-3; ICE-like apoptotic protease 3; CASP7
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond. Overexpression promotes programmed cell death.
PubMed ID:http://jpet.aspetjournals.org/content/295/1/328
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