Product Name: CBY1 Polyclonal Antibody, Cy5.5 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: Cy5.5
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human CBY1
Clonality: Polyclonal
CAS NO: 130964-39-5
Product: Itraconazole metabolite Hydroxy Itraconazole
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A; Protein chibby homolog 1; ARPP-binding protein; Cytosolic leucine-rich protein; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; CBY1; HRIHFB2025
Background: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
PubMed ID:http://jpet.aspetjournals.org/content/297/3/876
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