Product Name: CCDC134 Polyclonal Antibody, Cy3 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy3
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human CCDC134
Clonality: Polyclonal
CAS NO: 367273-07-2
Product: cGAMP
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: CC134_HUMAN; ccdc134; coiled-coil domain containing 134; Coiled-coil domain-containing protein 134; dJ821D11.3; FLJ22349; MGC21013.
Background: Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. CCDC134 (coiled-coil domain containing 134), also known as MGC21013 or FLJ22349, is a 229 amino acid protein encoded by a gene mapping to human chromosome 22.
PubMed ID:http://jpet.aspetjournals.org/content/298/3/964
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