Onments. Moreover, their importance has been increasingly noted since anti-inflammatory, antitumor

Onments. Moreover, their importance has been increasingly noted since anti-inflammatory, antitumor promoting and antiviral properties were described (Table 1). Many reports have been published about compounds isolated from macroalgae, namely, both intracellular and extracellular GLs as antitumor agents [41,42]. Recently, a great deal of interest has been expressed regarding compounds from macroalgae as potential antiviral [42?4] and anti-inflammatory products [41,45?7]. In the last two decades, the number of studies of GLs displayed by macroalgae has been increasing, as well as those on non-polar lipids and other compounds for halophytes [2,48,49]. In contrast, polar lipids in halophytes have been largely overlooked.Table 1. Bioactivity of polar lipids in several macrophytes species. A-836339 custom synthesis Species Name Green macroalgae Ulva fasciata Ulva armaricana Red macroalgae Chondria armata Chondrus crispus (cultured) Galaxoura cylindriea Laurencia papillose Osmundaria obtusiloba Palmaria palmate Solieria chordalis Brown macroalgae Dilophys fasciola Fucus spiralis Sargassum horneri Sargassum thumbergii Sargassum wightii Taonia atomaria SQDG MGDG SQDG, DGDG MGDG (20:5/18:4) and (18:3/18:4) SQDG SQDG Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) Anti-inflammatory Antitumor (Caco-2 cell) Antifungal (Candida albicans) Antimicrobial (X. oryzae pv.) Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) [42] [47] [51] [52] [53] [42] SQDG SQDG SQDG SQDG, PG MGDG (14:0/16:1) MGDG (20:5/16:0) Antifungal (C. albicans, Antimicrobial (Klebsiella sp.) Anti-inflammatory Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) anti-viral (HSV-1 and HSV-2) Anti-inflammatory Anti-tumor (NSCLC-N6 CELLS) [43] [45] [42] [42] [44] [46] [50] SQDG DGDG (14:0/18:3) Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) Antitumor (NSCLC-N6 CELLS) [42] [50] Lipid Class/Extract Bioactivity Ref.Mar. Drugs 2016, 14,7 ofTable 1. Cont. Species Name Seagrass Cymodocea serrulata Halophila ovalis Halophila stipulacea Mar. Drugs 2016, 14, xSeagrass Cymodocea serrulata Halodule pinifoliaLipid Class/ExtractBioactivity Antimicrobial (P. aeruginosa and K. pneumoniae) Antimicrobial (E. coli) Antimicrobial (V. cholera) Antimicrobial (S. bodii) Antimicrobial (S. aureus) Antimicrobial (P. aeruginosa and Antimicrobial (S. purchase Stattic aureus, K. K. pneumoniae) pneumoniae and S. paratyphi) Antimicrobial (E. coli) Antimicrobial (S. paratyphi) Antimicrobial (V. cholera) Antimicrobial (B. cereus) Antimicrobial (S. bodii) Antimicrobial (S. aureus) Antimicrobial (S. typhimurium) Antimicrobial (S. aureus, Anti-inflammatoryK. pneumoniae and S. paratyphi) Antimicrobial (S. paratyphi) Antimicrobial (B. cereus) Antimicrobial (S. typhimurium) AntiinflammatoryRef.Chloroform extract Methanolic extract Methanolic extract Chloroform extract Methanolic extractChloroform extract[54] [55]7 of[54] [55]Methanolic extract[54] [55] [54] [55] [54] [55] [56][54] [55] [56]ZosteraHalophila ovalis capensis Halophila stipulaceaMethanolic extract Methanolic extract Methanolic extract Ethyl acetate extract Chloroform extract Methanolic extract extract Ethyl acetateZostera Halodule pinifolia japonicaZostera capensisMethanolic extract Methanolic extractMethanolic extract Ethyl acetate extract Ethyl acetate extract Methanolic extract3.3. PhospholipidsZostera japoni.Onments. Moreover, their importance has been increasingly noted since anti-inflammatory, antitumor promoting and antiviral properties were described (Table 1). Many reports have been published about compounds isolated from macroalgae, namely, both intracellular and extracellular GLs as antitumor agents [41,42]. Recently, a great deal of interest has been expressed regarding compounds from macroalgae as potential antiviral [42?4] and anti-inflammatory products [41,45?7]. In the last two decades, the number of studies of GLs displayed by macroalgae has been increasing, as well as those on non-polar lipids and other compounds for halophytes [2,48,49]. In contrast, polar lipids in halophytes have been largely overlooked.Table 1. Bioactivity of polar lipids in several macrophytes species. Species Name Green macroalgae Ulva fasciata Ulva armaricana Red macroalgae Chondria armata Chondrus crispus (cultured) Galaxoura cylindriea Laurencia papillose Osmundaria obtusiloba Palmaria palmate Solieria chordalis Brown macroalgae Dilophys fasciola Fucus spiralis Sargassum horneri Sargassum thumbergii Sargassum wightii Taonia atomaria SQDG MGDG SQDG, DGDG MGDG (20:5/18:4) and (18:3/18:4) SQDG SQDG Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) Anti-inflammatory Antitumor (Caco-2 cell) Antifungal (Candida albicans) Antimicrobial (X. oryzae pv.) Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) [42] [47] [51] [52] [53] [42] SQDG SQDG SQDG SQDG, PG MGDG (14:0/16:1) MGDG (20:5/16:0) Antifungal (C. albicans, Antimicrobial (Klebsiella sp.) Anti-inflammatory Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) anti-viral (HSV-1 and HSV-2) Anti-inflammatory Anti-tumor (NSCLC-N6 CELLS) [43] [45] [42] [42] [44] [46] [50] SQDG DGDG (14:0/18:3) Antimicrobial (B. subtilis and E. coli) Antitumor (MCF-7 and HEPG2 cells) Antitumor (NSCLC-N6 CELLS) [42] [50] Lipid Class/Extract Bioactivity Ref.Mar. Drugs 2016, 14,7 ofTable 1. Cont. Species Name Seagrass Cymodocea serrulata Halophila ovalis Halophila stipulacea Mar. Drugs 2016, 14, xSeagrass Cymodocea serrulata Halodule pinifoliaLipid Class/ExtractBioactivity Antimicrobial (P. aeruginosa and K. pneumoniae) Antimicrobial (E. coli) Antimicrobial (V. cholera) Antimicrobial (S. bodii) Antimicrobial (S. aureus) Antimicrobial (P. aeruginosa and Antimicrobial (S. aureus, K. K. pneumoniae) pneumoniae and S. paratyphi) Antimicrobial (E. coli) Antimicrobial (S. paratyphi) Antimicrobial (V. cholera) Antimicrobial (B. cereus) Antimicrobial (S. bodii) Antimicrobial (S. aureus) Antimicrobial (S. typhimurium) Antimicrobial (S. aureus, Anti-inflammatoryK. pneumoniae and S. paratyphi) Antimicrobial (S. paratyphi) Antimicrobial (B. cereus) Antimicrobial (S. typhimurium) AntiinflammatoryRef.Chloroform extract Methanolic extract Methanolic extract Chloroform extract Methanolic extractChloroform extract[54] [55]7 of[54] [55]Methanolic extract[54] [55] [54] [55] [54] [55] [56][54] [55] [56]ZosteraHalophila ovalis capensis Halophila stipulaceaMethanolic extract Methanolic extract Methanolic extract Ethyl acetate extract Chloroform extract Methanolic extract extract Ethyl acetateZostera Halodule pinifolia japonicaZostera capensisMethanolic extract Methanolic extractMethanolic extract Ethyl acetate extract Ethyl acetate extract Methanolic extract3.3. PhospholipidsZostera japoni.