Product Name: C2orf16 Polyclonal Antibody, HRP Conjugated
Applications: WB, IHC-P
Reactivity: Human
Conjugation: HRP
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human C2orf16
Clonality: Polyclonal
CAS NO: 1195765-45-7
Product: GDC-0068
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Synonyms: Uncharacterized protein C2orf16; C2orf16
Background: C2orf16 (chromosome 2 open reading frame 16), also known as DKFZp434G118 or DKFZp781D2023, is a 1,984 amino acid protein encoded by a gene that maps to human chromosome 2p23.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
PubMed ID:http://jpet.aspetjournals.org/content/272/1/112
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