Product Name: C2orf24 Polyclonal Antibody
Applications: WB, IHC-P, IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human C2orf24
Clonality: Polyclonal
CAS NO: 872363-17-2
Product: Rofecoxib
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Synonyms: CDABP0125; CGI 57; chromosome 2 open reading frame 24; CNPD1_HUMAN; CNPPD1; Cyclin Pas1/PHO80 domain-containing protein 1; Protein CNPPD1.
Background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The C2orf24 gene product has been provisionally designated C2orf24 pending further characterization.
PubMed ID:http://jpet.aspetjournals.org/content/272/1/126
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