Product Name: C3orf39 Polyclonal Antibody, Cy3 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy3
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human C3orf39
Clonality: Polyclonal
CAS NO: 943319-70-8
Product: DMP 777
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: AGO61; Chromosome 3 open reading frame 39; FLJ14566; Uncharacterized glycosyltransferase AGO61 precursor; GTDC2_HUMAN.
Background: C3orf39, also known as AGO61, is a 580 amino acid secreted protein belonging to the glycosyltransferase 61 family. C3orf39 is encoded by a gene that maps to human chromosome 3p25.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
PubMed ID:http://jpet.aspetjournals.org/content/275/1/31
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