Product Name: C8orf77 Polyclonal Antibody, Cy3 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: Cy3
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human C8orf77
Clonality: Polyclonal
CAS NO: 19983-44-9
product targets : Cholecystokinin Receptor inhibitors
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Chromosome 8 open reading frame 77; MGC141859; Putative uncharacterized protein C8orf77;ZNFS1_HUMAN.
Background: C8orf77 (chromosome 8 open reading frame 77) is a 211 amino acid protein encoded by a gene that maps to human chromosome 8q24.3. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
PubMed ID:http://jpet.aspetjournals.org/content/284/1/258
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