Product Name: CBX5 (Tyr37) Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 488
Host: Rabbit
Sourcr: KLH conjugated synthetic phosphopeptide derived from human CBX5 around the phosphorylation site of Tyr37
Clonality: Polyclonal
CAS NO: 1073154-85-4
Product: Ritonavir metabolite Desthiazolylmethyloxycarbonyl Ritonavir
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Antigen p25; Cbx 5; Cbx5; CBX5_HUMAN; CG8409; Chromobox homolog 5 Drosophila HP1 alpha; Chromobox homolog 5 HP1 alpha homolog Drosophila; Chromobox homolog 5 HP1 alpha homolog, Drosophila; chromobox homolog 5; HP1 alpha homolog; Chromobox protein homolog 5; Chromobox protein homologue 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1; HP 1; HP 1A; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha; Suvar205; HP1a; HP1Hs-alpha; HP1 alpha; Antigen p25; Heterochromatin protein 1 homolog alpha.
Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].
PubMed ID:http://jpet.aspetjournals.org/content/297/3/1113
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