Product Name: Calcyphosine 2/CAPS2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 488
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human Calcyphosine 2/CAPS2
Clonality: Polyclonal
CAS NO: 81-23-2
Product: TAK-220
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Calcyphosin 2; Calcyphosin-2; Calcyphosine-2; Calcyphosine2; Calcyphosphine 2; CAPS 2; CAPS2; CAYP2_HUMAN; D630005B03Rik; FLJ34520; OTTHUMP00000202412; OTTMUSP00000027695; UG0636c06.
Background: CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
PubMed ID:http://jpet.aspetjournals.org/content/289/1/587
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