Product Name: cblA Polyclonal Antibody, Biotin Conjugated
Applications: WB, IHC-P
Reactivity: Human, Mouse, Rat
Conjugation: Biotin
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human MMAA/cblA
Clonality: Polyclonal
CAS NO: 210344-95-9
Product: PF 05089771
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: mitochondrial; cblA; MMAA protein; Methylmalonic aciduria cobalamin deficiency cblA type; Methylmalonic aciduria cobalamin deficiency type A; Methylmalonic aciduria type A protein; Methylmalonic aciduria type A protein mitochondrial; MMAA; MMAA_HUMAN.
Background: The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria. [provided by RefSeq, Jul 2008].
PubMed ID:http://jpet.aspetjournals.org/content/297/2/638
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