Product Name :
Fosravuconazole L-lysine ethanolate
Description:
Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a prodrug of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used for candidiasis, onychomycosis and parasitemia research.
CAS:
914361-45-8
Molecular Weight:
739.73
Formula:
C31H40F2N7O8PS
Chemical Name:
({[(2S,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl]oxy}methoxy)phosphonic acid; 2,6-diaminohexanoic acid; ethanol
Smiles :
C[C@@H](C1=NC(=CS1)C1C=CC(=CC=1)C#N)[C@](CN1C=NC=N1)(OCOP(O)(O)=O)C1=CC=C(F)C=C1F.CCO.NCCCCC(N)C(O)=O
InChiKey:
VOWYGLHOVNSCSA-GBTIKMTQSA-N
InChi :
InChI=1S/C23H20F2N5O5PS.C6H14N2O2.C2H6O/c1-15(22-29-21(10-37-22)17-4-2-16(9-26)3-5-17)23(11-30-13-27-12-28-30,34-14-35-36(31,32)33)19-7-6-18(24)8-20(19)25;7-4-2-1-3-5(8)6(9)10;1-2-3/h2-8,10,12-13,15H,11,14H2,1H3,(H2,31,32,33);5H,1-4,7-8H2,(H,9,10);3H,2H2,1H3/t15-,23-;;/m0../s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Schisandrin} web|{Schisandrin} Autophagy|{Schisandrin} Protocol|{Schisandrin} References|{Schisandrin} supplier|{Schisandrin} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a prodrug of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used for candidiasis, onychomycosis and parasitemia research.|Product information|CAS Number: 914361-45-8|Molecular Weight: 739.73|Formula: C31H40F2N7O8PS|Chemical Name: ({[(2S,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl]oxy}methoxy)phosphonic acid; 2,6-diaminohexanoic acid; ethanol|Smiles: C[C@@H](C1=NC(=CS1)C1C=CC(=CC=1)C#N)[C@](CN1C=NC=N1)(OCOP(O)(O)=O)C1=CC=C(F)C=C1F.CCO.NCCCCC(N)C(O)=O|InChiKey: VOWYGLHOVNSCSA-GBTIKMTQSA-N|InChi: InChI=1S/C23H20F2N5O5PS.{{Omaveloxolone} medchemexpress|{Omaveloxolone} STING|{Omaveloxolone} Protocol|{Omaveloxolone} In Vivo|{Omaveloxolone} custom synthesis|{Omaveloxolone} Cancer} C6H14N2O2.C2H6O/c1-15(22-29-21(10-37-22)17-4-2-16(9-26)3-5-17)23(11-30-13-27-12-28-30,34-14-35-36(31,32)33)19-7-6-18(24)8-20(19)25;7-4-2-1-3-5(8)6(9)10;1-2-3/h2-8,10,12-13,15H,11,14H2,1H3,(H2,31,32,33);5H,1-4,7-8H2,(H,9,10);3H,2H2,1H3/t15-,23-;;/m0../s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (67.PMID:23935843 59 mM; Need ultrasonic). H2O : Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Fosravuconazole has potent in vitro antifungal activity against a wide range of fungal species, including Candida, Aspergillus, and Trichophyton species.|In Vivo:|Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) treatment suppresses the parasitemia and prevents death in mice infected with the T. cruzi Y strain.|Products are for research use only. Not for human use.|
