Product Name :
ABT-046
Description:
ABT-046 is a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase 1. Oral administration of ABT-046 at doses ≥0.03 mg/kg significantly reduced postprandial triglycerides in mice following an oral lipid challenge. Further assessment in both acute and chronic safety pharmacology and toxicology studies demonstrated a clean profile up to high plasma levels.
CAS:
1031336-60-3
Molecular Weight:
350.41
Formula:
C20H22N4O2
Chemical Name:
2-[4-(4-{7-aminopyrazolo[1,5-a]pyrimidin-6-yl}phenyl)cyclohexyl]acetic acid
Smiles :
NC1=C(C=NC2=CC=NN21)C1C=CC(=CC=1)C1CCC(CC(O)=O)CC1
InChiKey:
BWUXSHHOKODNAK-UHFFFAOYSA-N
InChi :
InChI=1S/C20H22N4O2/c21-20-17(12-22-18-9-10-23-24(18)20)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-19(25)26/h5-10,12-14H,1-4,11,21H2,(H,25,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Datopotamab deruxtecan} medchemexpress|{Datopotamab deruxtecan} Immunology/Inflammation|{Datopotamab deruxtecan} Biological Activity|{Datopotamab deruxtecan} Formula|{Datopotamab deruxtecan} manufacturer|{Datopotamab deruxtecan} Epigenetic Reader Domain}
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
ABT-046 is a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase 1. Oral administration of ABT-046 at doses ≥0.{{Acacetin} MedChemExpress|{Acacetin} Apoptosis|{Acacetin} Protocol|{Acacetin} In Vitro|{Acacetin} supplier|{Acacetin} Autophagy} 03 mg/kg significantly reduced postprandial triglycerides in mice following an oral lipid challenge.PMID:23539298 Further assessment in both acute and chronic safety pharmacology and toxicology studies demonstrated a clean profile up to high plasma levels.|Product information|CAS Number: 1031336-60-3|Molecular Weight: 350.41|Formula: C20H22N4O2|Chemical Name: 2-[4-(4-{7-aminopyrazolo[1,5-a]pyrimidin-6-yl}phenyl)cyclohexyl]acetic acid|Smiles: NC1=C(C=NC2=CC=NN21)C1C=CC(=CC=1)C1CCC(CC(O)=O)CC1|InChiKey: BWUXSHHOKODNAK-UHFFFAOYSA-N|InChi: InChI=1S/C20H22N4O2/c21-20-17(12-22-18-9-10-23-24(18)20)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-19(25)26/h5-10,12-14H,1-4,11,21H2,(H,25,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
