Product Name :
Amino-PEG11-amine
Description:
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.
CAS:
479200-82-3
Molecular Weight:
544.68
Formula:
C24H52N2O11
Chemical Name:
3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane-1,35-diamine
Smiles :
NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
InChiKey:
TZQCFDTWLKAGLL-UHFFFAOYSA-N
InChi :
InChI=1S/C24H52N2O11/c25-1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-21-23-37-24-22-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-26/h1-26H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.|Product information|CAS Number: 479200-82-3|Molecular Weight: 544.68|Formula: C24H52N2O11|Chemical Name: 3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane-1,35-diamine|Smiles: NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN|InChiKey: TZQCFDTWLKAGLL-UHFFFAOYSA-N|InChi: InChI=1S/C24H52N2O11/c25-1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-21-23-37-24-22-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-26/h1-26H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Adenosine receptor antagonist 2} medchemexpress|{Adenosine receptor antagonist 2} Adenosine Receptor|{Adenosine receptor antagonist 2} Protocol|{Adenosine receptor antagonist 2} Formula|{Adenosine receptor antagonist 2} supplier|{Adenosine receptor antagonist 2} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Vigabatrin} web|{Vigabatrin} Neuronal Signaling|{Vigabatrin} Technical Information|{Vigabatrin} Data Sheet|{Vigabatrin} manufacturer|{Vigabatrin} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23715856 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
