Product Name :
(S)-GDC-1971
Description:
SHP2 inhibitor is an effective SHP2 allosteric inhibitors (IC50≤50 nM), blocking the activation of SHP2 by targeting the auto-inhibited conformation of SHP2 (WO2019183367A1, compound 118).
CAS:
2377352-48-0
Molecular Weight:
454.53
Formula:
C25H26N8O
Chemical Name:
Smiles :
N[C@H]1C2=CC=CC=C2OC21CCN(CC2)C1=CN=C2C(NN=C2N2CCCC3=NC=CC=C23)=N1
InChiKey:
RGCGBFIARQENML-QFIPXVFZSA-N
InChi :
InChI=1S/C25H26N8O/c26-22-16-5-1-2-8-19(16)34-25(22)9-13-32(14-10-25)20-15-28-21-23(29-20)30-31-24(21)33-12-4-6-17-18(33)7-3-11-27-17/h1-3,5,7-8,11,15,22H,4,6,9-10,12-14,26H2,(H,29,30,31)/t22-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Galcuronokinase} web|{Galcuronokinase} Apoptosis|{Galcuronokinase} Technical Information|{Galcuronokinase} Data Sheet|{Galcuronokinase} manufacturer|{Galcuronokinase} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{EN4} web|{EN4} c-Myc|{EN4} Technical Information|{EN4} Formula|{EN4} supplier|{EN4} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23800738
Additional information:
SHP2 inhibitor is an effective SHP2 allosteric inhibitors (IC50≤50 nM), blocking the activation of SHP2 by targeting the auto-inhibited conformation of SHP2 (WO2019183367A1, compound 118).|Product information|CAS Number: 2377352-48-0|Molecular Weight: 454.53|Formula: C25H26N8O|Smiles: N[C@H]1C2=CC=CC=C2OC21CCN(CC2)C1=CN=C2C(NN=C2N2CCCC3=NC=CC=C23)=N1|InChiKey: RGCGBFIARQENML-QFIPXVFZSA-N|InChi: InChI=1S/C25H26N8O/c26-22-16-5-1-2-8-19(16)34-25(22)9-13-32(14-10-25)20-15-28-21-23(29-20)30-31-24(21)33-12-4-6-17-18(33)7-3-11-27-17/h1-3,5,7-8,11,15,22H,4,6,9-10,12-14,26H2,(H,29,30,31)/t22-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Taylor Alexander, et al. SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF. WO2019183367A1Products are for research use only. Not for human use.|
