Product Name :
Talibegron hydrochloride
Description:
Talibegron hydrochloride (ZD2079 hydrochloride) is a potent β3-adrenoceptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Talibegron hydrochloride has potent vasorelaxant effect.
CAS:
178600-17-4
Molecular Weight:
351.82
Formula:
C18H22ClNO4
Chemical Name:
2-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethoxy)phenyl]acetic acid; chlorohydrogen
Smiles :
Cl.{{Gatifloxacin} medchemexpress|{Gatifloxacin} Topoisomerase|{Gatifloxacin} Purity & Documentation|{Gatifloxacin} Description|{Gatifloxacin} manufacturer|{Gatifloxacin} Cancer} OC(=O)CC1C=CC(=CC=1)OCCNC[C@H](O)C1C=CC=CC=1
InChiKey:
KCEFVYIWOQSJCH-LMOVPXPDSA-N
InChi :
InChI=1S/C18H21NO4.ClH/c20-17(15-4-2-1-3-5-15)13-19-10-11-23-16-8-6-14(7-9-16)12-18(21)22;/h1-9,17,19-20H,10-13H2,(H,21,22);1H/t17-;/m0./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Talibegron hydrochloride (ZD2079 hydrochloride) is a potent β3-adrenoceptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Talibegron hydrochloride has potent vasorelaxant effect.|Product information|CAS Number: 178600-17-4|Molecular Weight: 351.82|Formula: C18H22ClNO4|Synonym:|ZD2079 hydrochloride|Chemical Name: 2-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethoxy)phenyl]acetic acid; chlorohydrogen|Smiles: Cl.OC(=O)CC1C=CC(=CC=1)OCCNC[C@H](O)C1C=CC=CC=1|InChiKey: KCEFVYIWOQSJCH-LMOVPXPDSA-N|InChi: InChI=1S/C18H21NO4.{{Zotiraciclib} medchemexpress|{Zotiraciclib} JAK|{Zotiraciclib} Protocol|{Zotiraciclib} Formula|{Zotiraciclib} manufacturer|{Zotiraciclib} Autophagy} ClH/c20-17(15-4-2-1-3-5-15)13-19-10-11-23-16-8-6-14(7-9-16)12-18(21)22;/h1-9,17,19-20H,10-13H2,(H,21,22);1H/t17-;/m0./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23551549 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Talibegron hydrochloride (ZD2079 hydrochloride; 0.01-1000 μM) produces a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries and causes full relaxation with 1 mM.|References:|Hanna Kozłowska, et al. Atypical beta-adrenoceptors, different from beta 3-adrenoceptors and probably from the low-affinity state of beta 1-adrenoceptors, relax the rat isolated mesenteric artery. Br J Pharmacol. 2003 Sep;140(1):3-12.Products are for research use only. Not for human use.|
