Product Name :
RR6
Description:
RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively.
CAS:
1351758-37-6
Molecular Weight:
293.36
Formula:
C16H23NO4
Chemical Name:
(2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-4-phenylbutyl)butanamide
Smiles :
CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)CC1C=CC=CC=1
InChiKey:
PTVUGLNOPRZQEY-AWEZNQCLSA-N
InChi :
InChI=1S/C16H23NO4/c1-16(2,11-18)14(20)15(21)17-9-8-13(19)10-12-6-4-3-5-7-12/h3-7,14,18,20H,8-11H2,1-2H3,(H,17,21)/t14-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{SARS-CoV-2 S Protein RBD (HEK293)} MedChemExpress|{SARS-CoV-2 S Protein RBD (HEK293)} Biological Activity|{SARS-CoV-2 S Protein RBD (HEK293)} Data Sheet|{SARS-CoV-2 S Protein RBD (HEK293)} supplier|{SARS-CoV-2 S Protein RBD (HEK293)} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Isoniazid} MedChemExpress|{Isoniazid} Autophagy|{Isoniazid} Technical Information|{Isoniazid} Formula|{Isoniazid} manufacturer|{Isoniazid} Epigenetic Reader Domain}
Additional information:
RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively.|Product information|CAS Number: 1351758-37-6|Molecular Weight: 293.PMID:34235739 36|Formula: C16H23NO4|Chemical Name: (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-4-phenylbutyl)butanamide|Smiles: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)CC1C=CC=CC=1|InChiKey: PTVUGLNOPRZQEY-AWEZNQCLSA-N|InChi: InChI=1S/C16H23NO4/c1-16(2,11-18)14(20)15(21)17-9-8-13(19)10-12-6-4-3-5-7-12/h3-7,14,18,20H,8-11H2,1-2H3,(H,17,21)/t14-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (340.88 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Oral administration of RR6 in Wistar rats (150-200 g) completely inhibited plasma vanin activity and caused alterations of plasma lipid concentrations upon fasting. RR6 at 3 mg/mL in rats caused a nearly complete inhibition of plasma vanin.|Products are for research use only. Not for human use.|
