Product Name :
K-115 free base
Description:
Ripasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.
CAS:
223645-67-8
Molecular Weight:
323.39
Formula:
C15H18FN3O2S
Chemical Name:
4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline
Smiles :
C[C@H]1CNCCCN1S(=O)(=O)C1=CC=CC2=CN=CC(F)=C21
InChiKey:
QSKQVZWVLOIIEV-NSHDSACASA-N
InChi :
InChI=1S/C15H18FN3O2S/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14/h2,4-5,9-11,17H,3,6-8H2,1H3/t11-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Saquinavir} web|{Saquinavir} HIV|{Saquinavir} Technical Information|{Saquinavir} References|{Saquinavir} custom synthesis|{Saquinavir} Cancer}
Additional information:
Ripasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.{{Romosozumab} MedChemExpress|{Romosozumab} Protocol|{Romosozumab} Purity|{Romosozumab} manufacturer|{Romosozumab} Epigenetics} |Product information|CAS Number: 223645-67-8|Molecular Weight: 323.PMID:23074147 39|Formula: C15H18FN3O2S|Synonym:|Ripasudil free base|K 115 free base|K115 free base|Chemical Name: 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline|Smiles: C[C@H]1CNCCCN1S(=O)(=O)C1=CC=CC2=CN=CC(F)=C21|InChiKey: QSKQVZWVLOIIEV-NSHDSACASA-N|InChi: InChI=1S/C15H18FN3O2S/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14/h2,4-5,9-11,17H,3,6-8H2,1H3/t11-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
