Product Name :
Bufarenogin
Description:
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation.
CAS:
17008-65-0
Molecular Weight:
416.51
Formula:
C24H32O6
Chemical Name:
5-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11S,11aS)-3a,7,11-trihydroxy-9a,11a-dimethyl-10-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2H-pyran-2-one
Smiles :
C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2C(=O)[C@@H](O)[C@]2(C)[C@H](CC[C@@]21O)C1=COC(=O)C=C1
InChiKey:
SOGONHOGEFLVPE-PUVOGLICSA-N
InChi :
InChI=1S/C24H32O6/c1-22-9-7-15(25)11-14(22)4-5-17-19(22)20(27)21(28)23(2)16(8-10-24(17,23)29)13-3-6-18(26)30-12-13/h3,6,12,14-17,19,21,25,28-29H,4-5,7-11H2,1-2H3/t14-,15+,16-,17-,19-,21-,22+,23+,24+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{SMARCA2/4-IN-2} MedChemExpress|{SMARCA2/4-IN-2} PROTAC|{SMARCA2/4-IN-2} NF-κB|{SMARCA2/4-IN-2} Protocol|{SMARCA2/4-IN-2} Data Sheet|{SMARCA2/4-IN-2} manufacturer}
Shelf Life:
≥12 months if stored properly.{{Ruxolitinib} web|{Ruxolitinib} Protein Tyrosine Kinase/RTK|{Ruxolitinib} Biological Activity|{Ruxolitinib} In Vivo|{Ruxolitinib} manufacturer|{Ruxolitinib} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23773119
Additional information:
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation.|Product information|CAS Number: 17008-65-0|Molecular Weight: 416.51|Formula: C24H32O6|Chemical Name: 5-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11S,11aS)-3a,7,11-trihydroxy-9a,11a-dimethyl-10-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2H-pyran-2-one|Smiles: C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2C(=O)[C@@H](O)[C@]2(C)[C@H](CC[C@@]21O)C1=COC(=O)C=C1|InChiKey: SOGONHOGEFLVPE-PUVOGLICSA-N|InChi: InChI=1S/C24H32O6/c1-22-9-7-15(25)11-14(22)4-5-17-19(22)20(27)21(28)23(2)16(8-10-24(17,23)29)13-3-6-18(26)30-12-13/h3,6,12,14-17,19,21,25,28-29H,4-5,7-11H2,1-2H3/t14-,15+,16-,17-,19-,21-,22+,23+,24+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Bufarenogin induced intrinsic apoptosis through the cooperation of Bax and adenine‐nucleotide translocator and inhibited the metastasis and growth of orthotopical CRC cells.|Products are for research use only. Not for human use.|
