Product Name :
WYE-354
CAS No.:
1062169-56-5
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=N[N]3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5
Product Description :
WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) not P-AKT(T308), selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
Formula:
C24H29N7O5
Molecular Weight :
495.53
Synonyms:
Additional Information:
|CAS No. 1062169-56-5 ; |Formula C24H29N7O5 ; |Molecular Weight 495.53 ; |SMILES COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=N[N]3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5 ; |Target mTOR ; |Product Description WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) not P-AKT(T308), selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).{{404-86-4} site|{404-86-4} Purity & Documentation|{404-86-4} Description|{404-86-4} supplier} ; |Purity > 97% ; |Shipping Shipped on dry ice.{{149647-78-9} medchemexpress|{149647-78-9} Protocol|{149647-78-9} Formula|{149647-78-9} custom synthesis} ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO
