Product Name :
Anti-CA9, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-CA9, Human antibody is designed for detecting human CA9 specifically. Based on ELISA and/or FCM, Anti-CA9, Human antibody reacts with human CA9 specifically. | Immunogen: Recombinant human CA9 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human CA9 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane.{{1644670-37-0} MedChemExpress|{1644670-37-0} Technical Information|{1644670-37-0} Formula|{1644670-37-0} manufacturer} Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia.{{1541207-06-0} web|{1541207-06-0} Technical Information|{1541207-06-0} Formula|{1541207-06-0} manufacturer} Therefore, CA IX has become a reliable histochemical marker of hypoxia.PMID:30480972
Description2 :
Anti-CA9, Human antibody is designed for detecting human CA9 specifically. Based on ELISA and/or FCM, Anti-CA9, Human antibody reacts with human CA9 specifically.
Immunogen:
Recombinant human CA9
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.
