Product Name :
UV Cleavable Biotin-PEG2-Azide
Description:
UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1192802-98-4
Molecular Weight:
781.92
Formula:
C38H51N7O9S
Chemical Name:
1-{3-[({2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethyl}carbamoyl)methoxy]phenyl}-2-oxo-2-phenylethyl 6-azidohexanoate
Smiles :
[N-]=[N+]=NCCCCCC(=O)OC(C1=CC(=CC=C1)OCC(=O)NCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)C1C=CC=CC=1
InChiKey:
JHYKDGNZEADRIH-ZPIGJYFOSA-N
InChi :
InChI=1S/C38H51N7O9S/c39-45-42-17-8-2-5-16-34(48)54-37(36(49)27-10-3-1-4-11-27)28-12-9-13-29(24-28)53-25-33(47)41-19-21-52-23-22-51-20-18-40-32(46)15-7-6-14-31-35-30(26-55-31)43-38(50)44-35/h1,3-4,9-13,24,30-31,35,37H,2,5-8,14-23,25-26H2,(H,40,46)(H,41,47)(H2,43,44,50)/t30-,31-,35-,37?/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bevacizumab} MedChemExpress|{Bevacizumab} Protein Tyrosine Kinase/RTK|{Bevacizumab} Biological Activity|{Bevacizumab} Data Sheet|{Bevacizumab} custom synthesis|{Bevacizumab} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Artesunate} MedChemExpress|{Artesunate} Apoptosis|{Artesunate} Protocol|{Artesunate} In Vitro|{Artesunate} custom synthesis|{Artesunate} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32491456
Additional information:
UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1192802-98-4|Molecular Weight: 781.92|Formula: C38H51N7O9S|Chemical Name: 1-{3-[({2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethyl}carbamoyl)methoxy]phenyl}-2-oxo-2-phenylethyl 6-azidohexanoate|Smiles: [N-]=[N+]=NCCCCCC(=O)OC(C1=CC(=CC=C1)OCC(=O)NCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)C1C=CC=CC=1|InChiKey: JHYKDGNZEADRIH-ZPIGJYFOSA-N|InChi: InChI=1S/C38H51N7O9S/c39-45-42-17-8-2-5-16-34(48)54-37(36(49)27-10-3-1-4-11-27)28-12-9-13-29(24-28)53-25-33(47)41-19-21-52-23-22-51-20-18-40-32(46)15-7-6-14-31-35-30(26-55-31)43-38(50)44-35/h1,3-4,9-13,24,30-31,35,37H,2,5-8,14-23,25-26H2,(H,40,46)(H,41,47)(H2,43,44,50)/t30-,31-,35-,37?/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (127.89 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
