Product Name :
Isavuconazonium sulfate
Description:
Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis.
CAS:
946075-13-4
Molecular Weight:
814.84
Formula:
C35H36F2N8O9S2
Chemical Name:
1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-4-[1-({methyl[3-({[2-(methylamino)acetyl]oxy}methyl)pyridin-2-yl]carbamoyl}oxy)ethyl]-1H-1,2,4-triazol-4-ium hydrogen sulfate
Smiles :
CN(C1=NC=CC=C1COC(=O)CNC)C(=O)OC(C)[N+]1=CN(C[C@@](O)([C@@H](C)C2=NC(=CS2)C2C=CC(=CC=2)C#N)C2=CC(F)=CC=C2F)N=C1.[O-]S(O)(=O)=O
InChiKey:
LWXUIUUOMSMZKJ-KLFWAVJMSA-M
InChi :
InChI=1S/C35H35F2N8O5S.H2O4S/c1-22(33-42-30(18-51-33)25-9-7-24(15-38)8-10-25)35(48,28-14-27(36)11-12-29(28)37)19-45-21-44(20-41-45)23(2)50-34(47)43(4)32-26(6-5-13-40-32)17-49-31(46)16-39-3;1-5(2,3)4/h5-14,18,20-23,39,48H,16-17,19H2,1-4H3;(H2,1,2,3,4)/q+1;/p-1/t22-,23?,35+;/m0./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent.{{Belantamab mafodotin} MedChemExpress|{Belantamab mafodotin} Antibody-Drug Conjugates (ADCs)|{Belantamab mafodotin} Biological Activity|{Belantamab mafodotin} References|{Belantamab mafodotin} manufacturer|{Belantamab mafodotin} Autophagy} Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis.{{Dimethyl} site|{Dimethyl} Autophagy|{Dimethyl} Biological Activity|{Dimethyl} Formula|{Dimethyl} supplier|{Dimethyl} Cancer} |Product information|CAS Number: 946075-13-4|Molecular Weight: 814.PMID:32748124 84|Formula: C35H36F2N8O9S2|Chemical Name: 1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-4-[1-({methyl[3-({[2-(methylamino)acetyl]oxy}methyl)pyridin-2-yl]carbamoyl}oxy)ethyl]-1H-1,2,4-triazol-4-ium hydrogen sulfate|Smiles: CN(C1=NC=CC=C1COC(=O)CNC)C(=O)OC(C)[N+]1=CN(C[C@@](O)([C@@H](C)C2=NC(=CS2)C2C=CC(=CC=2)C#N)C2=CC(F)=CC=C2F)N=C1.[O-]S(O)(=O)=O|InChiKey: LWXUIUUOMSMZKJ-KLFWAVJMSA-M|InChi: InChI=1S/C35H35F2N8O5S.H2O4S/c1-22(33-42-30(18-51-33)25-9-7-24(15-38)8-10-25)35(48,28-14-27(36)11-12-29(28)37)19-45-21-44(20-41-45)23(2)50-34(47)43(4)32-26(6-5-13-40-32)17-49-31(46)16-39-3;1-5(2,3)4/h5-14,18,20-23,39,48H,16-17,19H2,1-4H3;(H2,1,2,3,4)/q+1;/p-1/t22-,23?,35+;/m0./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 166.67 mg/mL (204.54 mM; Need ultrasonic). H2O : 0.5 mg/mL (0.61 mM; ultrasonic and warming and heat to 60°C).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
