Product Name :
4′-Methoxychalcone
Description:
4′-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. 4′-Methoxychalcone modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity.
CAS:
959-23-9
Molecular Weight:
238.28
Formula:
C16H14O2
Chemical Name:
(2E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one
Smiles :
COC1C=CC(=CC=1)C(=O)/C=C/C1C=CC=CC=1
InChiKey:
KJHHAPASNNVTSN-KPKJPENVSA-N
InChi :
InChI=1S/C16H14O2/c1-18-15-10-8-14(9-11-15)16(17)12-7-13-5-3-2-4-6-13/h2-12H,1H3/b12-7+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
4′-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. 4′-Methoxychalcone modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity.|Product information|CAS Number: 959-23-9|Molecular Weight: 238.28|Formula: C16H14O2|Chemical Name: (2E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one|Smiles: COC1C=CC(=CC=1)C(=O)/C=C/C1C=CC=CC=1|InChiKey: KJHHAPASNNVTSN-KPKJPENVSA-N|InChi: InChI=1S/C16H14O2/c1-18-15-10-8-14(9-11-15)16(17)12-7-13-5-3-2-4-6-13/h2-12H,1H3/b12-7+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.X-GAL Autophagy |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.Bevacizumab Description |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|4′-Methoxychalcone (5 μM; 8 days) markedly increases the mRNA expression of adipogenic genes during adipocyte differentiation, PPARγ, aP2, FAS, adiponectin and GluT 4.PMID:32491442 4′-Methoxychalcone (5 μM; 8 days) reduces the upregulated mRNA expression of IL-6, PAI-1, and MCP-1 by TNF-α in preadipocyte 3T3-L1 cells. 4′-Methoxychalcone (5 μM; 0-8 days) causes an increase in PPARγ expression during differentiation, while C/EBPβ protein expression is relatively unaffected.|References:|Han Y, et al. Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells. Food Chem Toxicol. 2017 Aug;106(Pt A):17-24.Products are for research use only. Not for human use.|
