Product Name :
m-PEG5-NHS ester
Description:
m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
CAS:
874208-94-3
Molecular Weight:
377.39
Formula:
C16H27NO9
Chemical Name:
2,5-dioxopyrrolidin-1-yl 2,5,8,11,14-pentaoxaheptadecan-17-oate
Smiles :
COCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey:
FMMFVGSOBIANGY-UHFFFAOYSA-N
InChi :
InChI=1S/C16H27NO9/c1-21-6-7-23-10-11-25-13-12-24-9-8-22-5-4-16(20)26-17-14(18)2-3-15(17)19/h2-13H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 874208-94-3|Molecular Weight: 377.39|Formula: C16H27NO9|Chemical Name: 2,5-dioxopyrrolidin-1-yl 2,5,8,11,14-pentaoxaheptadecan-17-oate|Smiles: COCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O|InChiKey: FMMFVGSOBIANGY-UHFFFAOYSA-N|InChi: InChI=1S/C16H27NO9/c1-21-6-7-23-10-11-25-13-12-24-9-8-22-5-4-16(20)26-17-14(18)2-3-15(17)19/h2-13H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Dacomitinib custom synthesis |Shelf Life: ≥12 months if stored properly.Omaveloxolone custom synthesis |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32880480 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.Products are for research use only. Not for human use.|
