Product Name :
TLR7/8 agonist 4 hydroxy-PEG10-acid
Description:
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307).
CAS:
2388520-17-8
Molecular Weight:
837.01
Formula:
C41H68N6O12
Chemical Name:
1-(4-4-amino-2-butyl-1H-imidazo[4, 5-c]quinolin-8-ylpiperazin-1-yl)-3, 6, 9, 12, 15, 18, 21, 24, 27, 30-decaoxatritriacontan-33-oic acid
Smiles :
CCCCC1NC2=C(N=1)C(N)=NC1=CC=C(C=C12)N1CCN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)CC1
InChiKey:
LDGZEFQLJOSEED-UHFFFAOYSA-N
InChi :
InChI=1S/C41H68N6O12/c1-2-3-4-37-44-39-35-33-34(5-6-36(35)43-41(42)40(39)45-37)47-10-8-46(9-11-47)12-14-51-16-18-53-20-22-55-24-26-57-28-30-59-32-31-58-29-27-56-25-23-54-21-19-52-17-15-50-13-7-38(48)49/h5-6,33H,2-4,7-32H2,1H3,(H2,42,43)(H,44,45)(H,48,49)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307).|Product information|CAS Number: 2388520-17-8|Molecular Weight: 837.01|Formula: C41H68N6O12|Chemical Name: 1-(4-4-amino-2-butyl-1H-imidazo[4, 5-c]quinolin-8-ylpiperazin-1-yl)-3, 6, 9, 12, 15, 18, 21, 24, 27, 30-decaoxatritriacontan-33-oic acid|Smiles: CCCCC1NC2=C(N=1)C(N)=NC1=CC=C(C=C12)N1CCN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)CC1|InChiKey: LDGZEFQLJOSEED-UHFFFAOYSA-N|InChi: InChI=1S/C41H68N6O12/c1-2-3-4-37-44-39-35-33-34(5-6-36(35)43-41(42)40(39)45-37)47-10-8-46(9-11-47)12-14-51-16-18-53-20-22-55-24-26-57-28-30-59-32-31-58-29-27-56-25-23-54-21-19-52-17-15-50-13-7-38(48)49/h5-6,33H,2-4,7-32H2,1H3,(H2,42,43)(H,44,45)(H,48,49)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Mifepristone custom synthesis |Shelf Life: ≥12 months if stored properly.Calcipotriol In stock |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32491959 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|
