Product Name :
PI4KIIIbeta-IN-9
Description:
PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively.
CAS:
1429624-84-9
Molecular Weight:
487.59
Formula:
C23H25N3O5S2
Chemical Name:
N-(5-3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl-4-methyl-1,3-thiazol-2-yl)cyclopentanecarboxamide
Smiles :
CC1N=C(NC(=O)C2CCCC2)SC=1C1C=C(C(=CC=1)OC)S(=O)(=O)NC1C=CC(O)=CC=1
InChiKey:
KAXNDTMKFONXJM-UHFFFAOYSA-N
InChi :
InChI=1S/C23H25N3O5S2/c1-14-21(32-23(24-14)25-22(28)15-5-3-4-6-15)16-7-12-19(31-2)20(13-16)33(29,30)26-17-8-10-18(27)11-9-17/h7-13,15,26-27H,3-6H2,1-2H3,(H,24,25,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.TUNEL Apoptosis Detection Kit medchemexpress
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively.|Product information|CAS Number: 1429624-84-9|Molecular Weight: 487.59|Formula: C23H25N3O5S2|Chemical Name: N-(5-3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl-4-methyl-1,3-thiazol-2-yl)cyclopentanecarboxamide|Smiles: CC1N=C(NC(=O)C2CCCC2)SC=1C1C=C(C(=CC=1)OC)S(=O)(=O)NC1C=CC(O)=CC=1|InChiKey: KAXNDTMKFONXJM-UHFFFAOYSA-N|InChi: InChI=1S/C23H25N3O5S2/c1-14-21(32-23(24-14)25-22(28)15-5-3-4-6-15)16-7-12-19(31-2)20(13-16)33(29,30)26-17-8-10-18(27)11-9-17/h7-13,15,26-27H,3-6H2,1-2H3,(H,24,25,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (205.Daclatasvir medchemexpress 09 mM; Need ultrasonic).PMID:33269617 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PI4KIIIbeta-IN-9 (Compound 9) shows weak inhibition of PI3KC2γ (IC50 ~1 µM), PI3Kα (~2 µM), and PI4KIIIα (~2.6 µM) and Products are for research use only. Not for human use.|
