Product Name :
Rabbit anti-IL13RA1 Polyclonal Antibody(C-term)
Synonym :
Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD213a1; IL13RA1; IL13R; IL13RA
Host :
Rabbit
Species Reactivity:
Human
Specificity :
This IL13RA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 207-238 amino acids from the C-terminal region of human IL13RA1.
Predicted Reactivity:
Applications :
WB~~1:1000
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Immunology;Signal Transduction
Background :
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
UniProt :
P78552
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Purified Rabbit Polyclonal Antibody (Pab) |Synonym Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD213a1; IL13RA1; IL13R; IL13RA |Host Rabbit |Specificity This IL13RA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 207-238 amino acids from the C-terminal region of human IL13RA1. |Species Reactivity Human |Applications WB~~1:1000 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Research areas Immunology;Signal Transduction |Target |Background Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |Cellular localization Membrane; Single-pass type I membrane protein |UniProt P78552 |References |References Miloux B.,et al.FEBS Lett. 401:163-166(1997).Gauchat J.-F.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.Aman M.J.,et al.J. Biol. Chem. 271:29265-29270(1996).Wada M.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004). |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-IL13RA1 Polyclonal Antibody(C-term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
305335-31-3 In stock 53179-13-8 web PMID:29999877 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
